Missouri State University, Springfield, MO 65897
Pulsed Laser Synthesized Gold and Cobalt Nanoparticles for Biomedical Applications, Austin M. Shearin, H. Bhatta, A. Wanekaya, R. Delong, K. Ghosh*,Missouri State University, Physics, Astronomy, and Materials Science, Springfield, MO 65897, KartikGhosh@MissouriState.edu
Nanomaterials research has become a major attraction in the field of advanced materials research in the area of Physics, Chemistry, and Materials Science. Bio-compatible and chemically stable metal nanoparticles have biomedical applications that includes drug delivery, cell and DNA separation, gene cloning, magnetic resonance imaging (MRI). This research is aimed at the fabrication of nonmagnetic gold and magnetic cobalt nanoparticles using a safe, cost effective, and easy to handle technique that is capable of producing nanoparticles free of any contamination. Gold and cobalt nanoparticles have been synthesized at room temperature using cobalt and gold foil by pulsed laser ablation technique. These nanoparticles were characterized using UV-Visible (UV-Vis) spectroscopy, Field Emission Scanning Electron microscopy (FESEM), and dynamic laser light scattering (DLLS). The nanoparticles were stabilized in glucose solutions of various concentrations in deionized water. The presence of UV-Vis absorption peak at 525 nm for gold and at 270 nm for Co validates the nature of gold and cobalt nanoparticles, respectively. The DLLS size distributions of nanoparticles are in the range of 110 to 300 nm, which further confirms the presence nanoparticles. This work is partially supported by National Science Foundation (DMR- 0907037) and the National Cancer Institute (1 R15 CA139390-01).
[Abstract (DOCX)]